Greater Philadelphia is home to the nation's second-ranked life science cluster thanks to its existing and growing assets in academic research, global pharmaceuticals, biotech and device and diagnostic companies. Add some of the largest and most decorated health care networks in the country and some of the most well-respected medical schools in the world, and it's hard to overestimate the industry's impact here. A far-reaching support network for entrepreneurs has paid off with a large class of emerging startups. BioAdvance, a regional funder of industry startups, is one of the nation's leading investors providing pre-seed and seed-stage funding. University City Science Center is the oldest and largest urban research park and is consistently growing. PennsylvaniaBio, the state's leading biosciences organization, is headquartered in Malvern and has coordinated efforts to strengthen Greater Philadelphia's life sciences infrastructure.